Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
W. Jiang, Y. Cao, Y. Xue, Y. Ji, B. Y. Winer, M. Zhang, N. S. Singhal, J. Pierce, S. Chen, D. K. Ma
This study shows that targeting the VHL-HIF axis suppresses mortality and cellular damage caused by APOE4 and other stressors in C. elegans and mice.
bioRxiv · Feb 28, 2024 · PreprintPhysiology
W. I. Jiang, H. D. Belly, B. K. Wang, A. Wong, M. Kim, F. Oh, J. DeGeorge, X. Huang, S. Guang, O. K. Weiner, D. K. Ma
This study shows early-life thermal stress increases TSP-1 in C. elegans, leading to longevity and resilience through tetraspanin web formation.
bioRxiv · Jul 25, 2023Physiology
T. Pandey, B. Wang, C. Wang, J. Zu, H. Deng, K. Shen, G. Vale, J. G. McDonald, D. K. Ma
This study identifies LPD-3 as a megaprotein that regulates insulin-mTOR signaling and aging in C. elegans by modulating sphingolipid and insulin pathways.
bioRxiv · Feb 14, 2023 · PreprintPhysiology
C. Wang, B. Wang, T. Pandey, Y. Long, J. Zhang, F. Oh, J. Sima, R. Guo, Y. K. Liu, C. Zhang, S. Mukherjee, M. C. Bassik, W. Lin, H. Deng, G. Vale, , D. K. Ma
This paper identifies LPD-3 as a conserved megaprotein critical for lipid trafficking between ER and PM, essential for cold resilience in C. elegans and other species.
bioRxiv · Aug 25, 2022 · PreprintCell Biology
Z. Zhang, S. Luo, G. O. Barbosa, M. Bai, T. Kornberg, D. K. Ma
This study identifies TMEM39 as a conserved ER protein that facilitates collagen secretion and prevents ER stress by interacting with COPII components.
bioRxiv · Aug 17, 2020Cell Biology
N. S. Singhal, M. Bai, E. M. Lee, S. Luo, K. R. Cook, D. K. Ma
This study identifies a naturally occurring ATP5G1 variant in Arctic ground squirrels that enhances mitochondrial function and cell resilience to metabolic stress through a specific amino acid substitution.
bioRxiv · Jan 31, 2020 · PreprintCell Biology
Z. Zhang, M. Bai, G. O. Barbosa, A. Chen, Y. Wei, S. Luo, X. Wang, B. Wang, T. Tsukui, H. LI, D. Sheppard, T. Kornberg, D. K. Ma
This study identifies TMEM-131 family proteins as conserved regulators of collagen assembly and secretion across species, showing their role in ER stress and collagen production.
bioRxiv · Oct 5, 2019Cell Biology
M. Bai, R. Vozdek, A. Hnizda, C. Jiang, B. Wang, L. Kuchar, T. Li, Y. Zhang, C. Wood, L. Feng, Y. Dang, D. K. Ma
This study identifies C. elegans MANF orthologue, shows it binds sulfatide, and demonstrates sulfatide-dependent cytoprotection in both worms and mammalian cells.
bioRxiv · Feb 11, 2018Cell Biology