Author

R. W. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. A. Benayoun· 2 shared C. Lee· 2 shared C. J. Mitchell· 1 shared C. R. Barr· 1 shared C. Y. Park· 1 shared D. Cameron-Smith· 1 shared E. Kim· 1 shared I. Cohen· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

B. A. Benayoun

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Author profile →

2 papers

Recent·Most cited

The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide

M. C. Rice, M. Imun, S. W. Jung, C. Y. Park, J. S. Kim, R. W. Lai, C. R. Barr, J. M. Son, K. Tor, E. Kim, R. J. Lu, I. Cohen, B. A. Benayoun, C. Lee

This study identifies MOTS-c, a mitochondrial-encoded host defense peptide with antibacterial and immunomodulatory functions, showing that the immune system is encoded by both nuclear and mitochondrial genomes.

bioRxiv · Mar 2, 2023 · PreprintImmunology

MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis

J. C. Reynolds, R. W. Lai, J. S. T. Woodhead, J. H. Joly, C. J. Mitchell, D. Cameron-Smith, R. Lu, P. Cohen, N. A. Graham, B. A. Benayoun, T. L. Merry, C. Lee

This study shows that MOTS-c, a mitochondrial-encoded peptide, improves physical performance and muscle homeostasis across ages in mice and humans, suggesting mitochondrial genes regulate aging.

bioRxiv · Dec 22, 2019Cell Biology