Author

B. A. Benayoun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:human· 2

Frequent Co-Authors

C. Lee· 2 shared R. W. Lai· 2 shared A. D. Smith· 1 shared A. Dickerson· 1 shared A. Moriarty· 1 shared A. Thomas· 1 shared B. Peng· 1 shared C. J. McGill· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

C. Lee

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide

M. C. Rice, M. Imun, S. W. Jung, C. Y. Park, J. S. Kim, R. W. Lai, C. R. Barr, J. M. Son, K. Tor, E. Kim, R. J. Lu, I. Cohen, B. A. Benayoun, C. Lee

This study identifies MOTS-c, a mitochondrial-encoded host defense peptide with antibacterial and immunomodulatory functions, showing that the immune system is encoded by both nuclear and mitochondrial genomes.

bioRxiv · Mar 2, 2023 · PreprintImmunology

Sex-dimorphic expression of extracellular matrix genes in mouse bone marrow neutrophils

C. J. McGill, C. Y. Ewald, B. A. Benayoun

The paper investigates sex-dimorphic expression of ECM genes in mouse bone marrow neutrophils using bulk and single-cell transcriptomics.

bioRxiv · Feb 25, 2023Immunology

Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis

O. Iriondo, D. Mecenas, Y. Li, C. R. Chin, A. Thomas, Y. Amzaleg, A. Moriarty, V. Ortiz, M. MacKay, A. Dickerson, G. Lee, S. Harotoonian, B. A. Benayoun, A. D. Smith, C. Mason, , M. Yu

The paper shows hypoxia induces a long-lasting suppression of type I interferon and antigen presentation in breast cancer cells, enhancing metastasis and being reversible with HDACi and immunotherapy.

bioRxiv · May 12, 2022 · PreprintCancer Biology

Adult fibroblasts use aggresomes only in distinct cell-states

C. S. Morrow, Z. P. Arndt, B. Peng, E. Y. Zewdie, B. A. Benayoun, D. L. Moore

The paper examines aggresome formation in primary adult mouse fibroblasts across different cell-states, finding it occurs only in quiescent and immortalized cells, not in proliferating or senescent cells.

bioRxiv · Jul 23, 2021Cell Biology

MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis

J. C. Reynolds, R. W. Lai, J. S. T. Woodhead, J. H. Joly, C. J. Mitchell, D. Cameron-Smith, R. Lu, P. Cohen, N. A. Graham, B. A. Benayoun, T. L. Merry, C. Lee

This study shows that MOTS-c, a mitochondrial-encoded peptide, improves physical performance and muscle homeostasis across ages in mice and humans, suggesting mitochondrial genes regulate aging.

bioRxiv · Dec 22, 2019Cell Biology