Author

R. Wufur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. Hu· 3 shared Y. Zhang· 3 shared F. Chen· 2 shared M. Xiao· 2 shared D. Lou· 1 shared G. Sun· 1 shared J. Feng· 1 shared J. Yuan· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

S. Hu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms

F. Chen, Q. Wang, M. Xiao, D. Lou, R. Wufur, S. Hu, Z. Zhang, Y. Wang, Y. Zhang

The paper identifies two Keap1 isoforms that interact with Smad2/3, enhancing their stability and transcriptional activity, and reveals a novel crosstalk between the Keap1-Nrf2 and TGF-β1-Smad2/3 pathways.

bioRxiv · Nov 22, 2022 · PreprintCell Biology

Different inhibition of Nrf2 by two Keap1 isoforms α and β to shape malignant behaviour of human hepatocellular carcinoma

F. Chen, M. Xiao, J. Feng, R. Wufur, K. Liu, S. Hu, Y. Zhang

This study investigates how two Keap1 isoforms, α and β, differentially inhibit Nrf2 and influence malignant behaviors in hepatocellular carcinoma.

bioRxiv · Jul 15, 2022Biochemistry

Distinct roles of Nrf1 and Nrf2 in monitoring the reductive stress response to dithiothreitol (DTT)

R. Wufur, Z. Fan, J. Yuan, Z. Zheng, S. Hu, G. Sun, Y. Zhang

This paper investigates the distinct roles of Nrf1 and Nrf2 in the reductive stress response to DTT, showing differential regulation of redox and ER stress defense genes.

bioRxiv · Jun 24, 2022Cell Biology