Author

R. Zweigerdt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. Jonigk· 2 shared H. Kempf· 2 shared A. Bezrouk· 1 shared A. Franke· 1 shared A. Ganser· 1 shared A. Haase· 1 shared A. Haverich· 1 shared A. Hilfiker· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

D. Jonigk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell therapy with human iPSC-derived cardiomyocyte aggregates leads to efficient engraftment and functional recovery after myocardial infarction in non-human primates

I. Gruh, A. Martens, S. Cebotari, A. Schrod, A. Haase, C. Halloin, W. Triebert, T. Goecke, M. Arar, K. Hoeffler, P. Frank, K. Lampe, A. Moussavi, V. Fricke, N. Kriedemann, , U. Martin

This study transplants human iPSC-derived cardiomyocyte aggregates into non-human primates with myocardial infarction, showing efficient engraftment and functional recovery with lower cell doses than previous single-cell approaches.

bioRxiv · Dec 31, 2023 · PreprintCell Biology

Targeted anti-BCR-ABL+ ALL therapy may benefit the heart

H. Kirchhoff, M. Ricke-Hoch, K. Wohlan, S. Pietzsch, U. Karsli, S. Erschow, R. Zweigerdt, A. Ganser, M. Eder, M. Scherr, D. Hilfiker-Kleiner

This paper shows that targeted therapies for BCR-ABL+ ALL can cause heart damage, but some treatments like dasatinib and venetoclax can reverse cardiac defects while others cannot.

bioRxiv · Jun 4, 2021 · PreprintCancer Biology

Scalable production of tissue-like vascularised liver organoids from human PSCs.

S. P. Harrison, R. Sillar, Y. Tanaka, Y. Xiang, B. Patterson, H. Kempf, E. Melum, K. Asrud, M. E. Chollet, E. Andersen, P. M. Sandset, S. Baumgarten, F. Bonanini, D. Kurek, S. Mathapati, , G. J. Sullivan

This paper develops a method to produce vascularised liver organoids from human PSCs without 2D patterning or ECM, demonstrating liver-like functions and cellular complexity.

bioRxiv · Dec 2, 2020 · PreprintCell Biology

Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis

B. Jaeger, J. C. Schupp, L. Plappert, O. Terwolbeck, G. Kayser, P. Engelhard, T. S. Adams, R. Zweigerdt, H. Kempf, S. Lienenklaus, W. Garrels, I. Nazarenko, D. Jonigk, M. Wygrecka, D. Klatt, , A. Prasse

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.

bioRxiv · Sep 4, 2020Cell Biology