Pneumococcus uses COMMD2 to alter host cellular immunity.
M. G. Connor, L. Sanchez, C. Chevalier, T. M. N. Camarasa, F. Carvalho, M. J. G. Eldridge, T. Chaze, M. Matondo, E. Karkeni, S. Dufour, F. Impens, S. Baumgarten, J. Enninga, M. A. Hamon
This study identifies COMMD2 as a bacterial factor that interacts with p65 and p62 to degrade p65, altering host cellular immunity during pneumococcal infection.
bioRxiv · Apr 8, 2022Microbiology