Author

J. C. Schupp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Assay:scRNA-seq· 5 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:CITE-seq· 1

Frequent Co-Authors

N. Kaminski· 5 shared T. S. Adams· 5 shared S. Poli· 3 shared A. C. Habermann· 2 shared A. J. Gutierrez· 2 shared C. Cosme· 2 shared D. Rassl· 2 shared I. O. Rosas· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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5 shared papersCell Biology

N. Kaminski

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma

J. Obacz, R. Nibhani, T. S. Adams, J. C. Schupp, J. A. Valer, N. Veale, G. Aresu, A. S. Coonar, A. Peryt, G. Biffi, N. Kaminski, H. E. Francies, D. Rassl, M. Garnett, R. C. Rintoul, S. J. Marciniak

This study presents a single-cell transcriptomic atlas of human pleura, identifying stromal heterogeneity and informing in vitro models of mesothelioma.

bioRxiv · Dec 3, 2022 · PreprintCancer Biology

Single Cell RNA-seq and Mass Cytometry Reveals a Novel and a Targetable Population of Macrophages in Idiopathic Pulmonary Fibrosis

E. A. Ayaub, S. Poli, J. Ng, T. S. Adams, J. C. Schupp, L. Quesada, F. Poli, C. Cosme, R. Matthew, J. Martinez, X. Liang, J. Villalba, J. A. Lederer, S. G. Chu, B. Raby, , I. Rosas

The paper identifies a novel, targetable macrophage population in idiopathic pulmonary fibrosis using single-cell RNA-seq, CyTOF, and flow cytometry.

bioRxiv · Jan 4, 2021 · PreprintCell Biology

Integrated Single Cell Atlas of Endothelial Cells of the Human Lung

J. C. Schupp, T. S. Adams, C. Cosme, M. S. Brickman Raredon, N. Omote, S. Poli, K.-A. Rose, E. Manning, M. Sauler, G. DeIuliis, F. Ahangari, N. Neumark, Y. Yuan, A. C. Habermann, A. J. Gutierrez, , N. Kaminski

The paper reanalyzes six scRNA-seq datasets to create a comprehensive reference atlas of human lung endothelial cells, identifying new subpopulations and confirming their conservation in mice.

bioRxiv · Oct 21, 2020Cell Biology

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

L. T. Bui, N. I. Winters, M.-I. Chung, C. Joseph, A. J. Gutierrez, A. C. Habermann, T. S. Adams, J. C. Schupp, S. Poli, L. M. Peter, C. J. Taylor, J. B. Blackburn, B. W. Richmond, A. G. Nicholson, D. Rassl, , Human Cell Atlas Lung Biological Network

The paper analyzes single-cell transcriptomes from healthy and chronic lung disease lungs to identify gene expression programs linked to SARS-CoV-2 entry and severity.

bioRxiv · Oct 20, 2020Cell Biology

Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis

B. Jaeger, J. C. Schupp, L. Plappert, O. Terwolbeck, G. Kayser, P. Engelhard, T. S. Adams, R. Zweigerdt, H. Kempf, S. Lienenklaus, W. Garrels, I. Nazarenko, D. Jonigk, M. Wygrecka, D. Klatt, , A. Prasse

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.

bioRxiv · Sep 4, 2020Cell Biology