Author

R.-J. Palstra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

S. Rao· 3 shared T. Mahmoudi· 3 shared C. Lungu· 2 shared T. W. Kan· 2 shared A. Bazrafshan· 1 shared A. Gorska· 1 shared A. Ngubane· 1 shared A. Verbon· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

S. Rao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SQuHIVLa: A novel assay for Specific Quantification of inducible HIV-1 reservoir by LAMP

T. Hossain, C. Lungu, S. de Schrijver, M. Kuali, S. Rao, A. Ngubane, T. W. Kan, R.-J. Palstra, P. Madlala, T. Ndung'u, T. Mahmoudi

SQuHIVLa quantifies inducible HIV-1 reservoirs in CD4+ T cells using a sensitive and specific RT-LAMP assay, showing high throughput and scalability.

bioRxiv · Jul 14, 2023 · PreprintMicrobiology

Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma

E. De Crignis, S. Romal, F. Carofiglio, P. Moulos, M. M. A. Verstegen, M. M. Khalid, F. Pourfarzad, S. Rao, A. Bazrafshan, C. Koutsothanassis, H. Gehart, T. W. Kan, R.-J. Palstra, C. Boucher, J. IJzermans, , T. Mahmoudi

This paper establishes human liver organoids as a model for HBV infection and HCC, showing they support viral replication, produce infectious HBV, and exhibit cancer-related gene signatures.

bioRxiv · Nov 11, 2020Cancer Biology

Induction of selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir

S. Rao, C. Lungu, R. Crespo, T. H. Steijaert, A. Gorska, R.-J. Palstra, H. A. B. Prins, W. van Ijcken, C. Rokx, Y. M. Mueller, J. J. A. Van Kampen, A. Verbon, P. D. Katsikis, C. A. B. Boucher, R. A. Gruters, T. Mahmoudi

This study shows DDX3 inhibitors induce selective apoptosis in HIV-1-infected cells, reducing the inducible latent HIV-1 reservoir.

bioRxiv · Aug 26, 2020Microbiology