Author

S. Romal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

T. W. Kan· 2 shared A. Bazrafshan· 1 shared A. Goodspeed· 1 shared A. Jean· 1 shared C. B. Tilton· 1 shared C. Boucher· 1 shared C. Deiter· 1 shared C. Koutsothanassis· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

T. W. Kan

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2 papers

Recent·Most cited

NPEPPS is a novel and druggable driver of platinum resistance

R. T. Jones, M. Scholtes, A. Goodspeed, M. M. Akbarzadeh, S. Mohapatra, L. E. Feldman, H. Vekony, A. Jean, C. B. Tilton, M. V. Orman, S. Romal, C. Deiter, T. W. Kan, N. Xander, S. Araki, , J. C. Costello

This study identifies NPEPPS as a driver of cisplatin resistance in bladder cancer and shows its inhibition can enhance cisplatin efficacy in preclinical models.

bioRxiv · Mar 4, 2021 · PreprintCancer Biology

Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma

E. De Crignis, S. Romal, F. Carofiglio, P. Moulos, M. M. A. Verstegen, M. M. Khalid, F. Pourfarzad, S. Rao, A. Bazrafshan, C. Koutsothanassis, H. Gehart, T. W. Kan, R.-J. Palstra, C. Boucher, J. IJzermans, , T. Mahmoudi

This paper establishes human liver organoids as a model for HBV infection and HCC, showing they support viral replication, produce infectious HBV, and exhibit cancer-related gene signatures.

bioRxiv · Nov 11, 2020Cancer Biology