Author

Rachel L. Lewis

Virginia Commonwealth University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Claire D. JamesiD· 3 shared Molly L. BristoliD· 3 shared Austin J. Witt· 2 shared Iain M. MorganiD· 2 shared Jenny D Roe· 2 shared Xu Wang· 2 shared Apurva Tadimari PrabhakariD· 1 shared Austin Witt· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Claire D. JamesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HPV16 recruitment of SMARCAL1 to viral and host replication forks is required for the viral life cycle

Claire D. James, Aya H. Youssef, Jenny D Roe, Floriana Cappiello, Francesca Antonella Aiello, Benedetta Perdichizzi, Rachel L. Lewis, Austin Witt, Apurva Tadimari Prabhakar, Xu Wang, Molly L. Bristol, Pietro Pichierri, Iain M. Morgan

This paper shows that HPV16 requires SMARCAL1 to recruit to viral and host replication forks, which is essential for its life cycle and prevents DNA damage and genome integration.

mBio · Mar 30, 2026Peer-reviewedMicrobiology

The Utility of Fibroblast Co-culture for the Maintenance of Episomes in Human Papillomavirus-Associated Cancer Models

Austin J. Witt, Rachel L. Lewis, Xu Wang, Phoebe V. Bridy, Jenny D Roe, Iain M. Morgan, Claire D. James, Molly L. Bristol

The paper shows that HPV16+ OPC cell lines lose episomal status in monoculture and proposes fibroblast co-culture to maintain episomal viral genomes.

mSphere · Feb 25, 2026Peer-reviewedCancer Biology

Fibroblasts Regulate the Transformation Potential of Human Papillomavirus-positive Keratinocytes

Claire D. James, Rachel L. Lewis, Austin J. Witt, Christiane Carter, Nabiha M. Rais, Xu Wang, Molly L. Bristol

This study shows fibroblasts support HPV RNA expression and episomal maintenance but reduce EMT-related expression in HPV+ keratinocytes.

Tumour Virus Research · Dec 10, 2024Peer-reviewedCancer Biology