Author

Austin J. Witt

Virginia Commonwealth University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Claire D. JamesiD· 3 shared Molly L. BristoliD· 3 shared Iain M. MorganiD· 2 shared Jenny D Roe· 2 shared Phoebe V. Bridy· 2 shared Rachel L. Lewis· 2 shared A. NguyeniD· 1 shared Ahmed DiabiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

Claire D. JamesORCID

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Author profile →

3 papers

Recent·Most cited

E2 displacement of CIP2A from TOPBP1 activates the DNA damage response during papillomavirus life cycles

Apurva Tadimari Prabhakar, Claire D. James, A. Nguyen, Phoebe V. Bridy, Xu Wang, Ryan J. Zoldork, Jenny D Roe, Austin J. Witt, Srimanya S. Panidepu, Sarita Giri, Molly L. Bristol, Krista Dalton, Andreas Wieland, Ahmed Diab, Anthony C. Faber, , Iain M. Morgan

This paper shows E2 activates the DNA damage response by displacing CIP2A from TOPBP1, promoting viral replication and cell proliferation through ATM activation and ATR inhibition.

Cell Reports · Oct 26, 2026Peer-reviewedCancer Biology

The Utility of Fibroblast Co-culture for the Maintenance of Episomes in Human Papillomavirus-Associated Cancer Models

Austin J. Witt, Rachel L. Lewis, Xu Wang, Phoebe V. Bridy, Jenny D Roe, Iain M. Morgan, Claire D. James, Molly L. Bristol

The paper shows that HPV16+ OPC cell lines lose episomal status in monoculture and proposes fibroblast co-culture to maintain episomal viral genomes.

mSphere · Feb 25, 2026Peer-reviewedCancer Biology

Fibroblasts Regulate the Transformation Potential of Human Papillomavirus-positive Keratinocytes

Claire D. James, Rachel L. Lewis, Austin J. Witt, Christiane Carter, Nabiha M. Rais, Xu Wang, Molly L. Bristol

This study shows fibroblasts support HPV RNA expression and episomal maintenance but reduce EMT-related expression in HPV+ keratinocytes.

Tumour Virus Research · Dec 10, 2024Peer-reviewedCancer Biology