Rachna Dherwani

Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through intrinsic apoptosis in the neonatal lung

This study identifies Stc1-expressing myofibroblasts as a distinct lineage that undergoes apoptosis during neonatal lung development, using genetic tools and single-cell RNA-seq.

Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling

This study identifies aberrant transitional alveolar epithelial cells in a mouse fibrosis model and shows they activate fibroblasts through a profibrotic secretome.