Loss of multi-level 3D genome organization during breast cancer progression
Roberto Rossini, Mohammadsaleh Oshaghi, Maxim Nekrasov, Aurélie Bellanger, Renae Domaschenz, Yasmin Dijkwel, Mohamed Abdelhalim, Rahul Agrawal, Marit Ledsaak, Philippe Collas, Ragnhild Eskeland, David John Tremethick, Jonas Paulsen
This study investigates how 3D genome organization changes during breast cancer progression using Hi-C and epigenomic data, revealing structural alterations linked to oncogenic gene activation.
Genome Research · Oct 9, 2025Peer-reviewedGenomics