Kinetic and Mechanistic Characterization of RSpFAST, A Non-Covalent Versatile Chemogenetic Platform for Fluorescence Imaging
Yuriy Shpinov, Mrinal Mandal, Vincent M.L. Van Deuren, Aliénor Lahlou, Matthias Le Bec, Raja Chouket, Chaima Hadj Moussa, Clara Bonin, Hessam Sepasi Tehrani, Ian Coghill, Lina El Hajji, Karim Ounoughi, Jaime Franco, Marie‐Aude Plamont, Philippe Pelupessy, , Ludovic Jullien
This paper introduces RSpFAST, a non-covalent chemogenetic platform for fluorescence imaging, and demonstrates its dual behavior as a stable label and a reversible photoswitcher.
Journal of the American Chemical Society · Aug 25, 2026Peer-reviewedBiochemistry