Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos
Andrew Hartley, Laura C.A. Galbraith, Robin Shaw, Amy J. Tibbo, Rajan Veeratterapillay, Laura Wilson, Rakesh Heer, Karen Blyth, Hing Y. Leung, Imran Ahmad
This study identifies Arid1a loss as a driver of aggressive prostate cancer in mice, accelerating tumorigenesis and promoting a proliferative, collagen-poor phenotype through cooperation with cFos.
British Journal of Cancer · Jan 30, 2025Peer-reviewedCancer Biology