Author

Hing Y. Leung

Cancer Research UK Scotland InstituteORCID 0000-0002-3933-3975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Imran AhmadiD· 2 shared Karen BlythiD· 2 shared Laura C.A. GalbraithiD· 2 shared Amy J. TibboiD· 1 shared Andrew HartleyiD· 1 shared Esther BaenaiD· 1 shared Georges LacaudiD· 1 shared Ivana SteineriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Imran AhmadORCID

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2 papers

Recent·Most cited

Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

Andrew Hartley, Laura C.A. Galbraith, Robin Shaw, Amy J. Tibbo, Rajan Veeratterapillay, Laura Wilson, Rakesh Heer, Karen Blyth, Hing Y. Leung, Imran Ahmad

This study identifies Arid1a loss as a driver of aggressive prostate cancer in mice, accelerating tumorigenesis and promoting a proliferative, collagen-poor phenotype through cooperation with cFos.

British Journal of Cancer · Jan 30, 2025Peer-reviewedCancer Biology

RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development

Renaud Mével, Ivana Steiner, Susan M. Mason, Laura C.A. Galbraith, Rahima Patel, Muhammad Zaki Hidayatullah Fadlullah, Imran Ahmad, Hing Y. Leung, Pedro Oliveira, Karen Blyth, Esther Baena, Georges Lacaud

This study identifies RUNX1 as a marker for a castration-resistant luminal lineage in the developing and adult mouse prostate, distinct from NKX3.1+ cells.

eLife · Oct 7, 2020Peer-reviewedDevelopmental Biology