Author

Laura C.A. Galbraith

Cancer Research UK Scotland InstituteORCID 0000-0002-1396-4226Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Karen BlythiD· 3 shared Hing Y. LeungiD· 2 shared Imran AhmadiD· 2 shared Robin ShawiD· 2 shared Adiba KhaniD· 1 shared Alessandra I. RiggioiD· 1 shared Alex L. Young· 1 shared Amy J. TibboiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

Karen BlythORCID

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3 papers

Recent·Most cited

Cancer BiologyBritish Journal of CancerPeer-reviewedMay 7, 2026

Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis

Alessandra I. Riggio, Kerri Sweeney, Robin Shaw…·Karen Blyth

This study shows that Runx1 and Runx2 suppress Wnt/β-catenin-driven mammary tumourigenesis, with combined loss leading to increased tumour development and oncogenic pathway activation.

1 citation

mousebulk RNA-seq

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Cancer BiologyBritish Journal of CancerPeer-reviewedJan 30, 2025

Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

Andrew Hartley, Laura C.A. Galbraith, Robin Shaw…·Imran Ahmad

This study identifies Arid1a loss as a driver of aggressive prostate cancer in mice, accelerating tumorigenesis and promoting a proliferative, collagen-poor phenotype through cooperation with cFos.

7 citations

mousebulk RNA-seq

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Developmental BiologyeLifePeer-reviewedOct 7, 2020

RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development

Renaud Mével, Ivana Steiner, Susan M. Mason…·Georges Lacaud

This study identifies RUNX1 as a marker for a castration-resistant luminal lineage in the developing and adult mouse prostate, distinct from NKX3.1+ cells.

46 citationstop 4%

mousescRNA-seq

𝕏 PostBluesky