A confirmatory, dual-centric non-human primate study on the efficacy of novel oropharyngeal spray immunization with an adenoviral vector vaccine against RSV -- Important lessons learned
Matthias Tenbusch, Gerrit Koopman, Petra Mooij, Berit Roshani, Pascal Irrgang, Dennis Lapuente, Ivanela I. Kondova, Willy M J M Bogers, Edmond J. Remarque, Ramona Vestweber, Samuel Alberto Mérida Ruíz, Nadine Krüger, S Meyer, Olaf Gefeller, Christiane Stahl‐Hennig, Klaus Überla
This study evaluates a DNA-adenoviral prime-boost vaccine for RSV in non-human primates, showing reduced viral replication but challenges in multi-centre trials.
bioRxiv · Apr 20, 2026 · PreprintImmunology