Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor
Qimeng Li, Ákos Nemecz, Gabriel Aymé, Gabrielle Dejean de la Bâtie, Marie S. Prevost, Stéphanie Pons, Nathalie Barilone, Rayen Baachaoui, Uwe Maskos, Pierre J. Lafaye, Pierre‐Jean Corringer
This paper describes the generation of nanobodies that act as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor, with distinct functional properties.
Cellular and Molecular Life Sciences · May 25, 2023Peer-reviewedNeuroscience