Author

Rea J Brakaj

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:imaging· 1

Frequent Co-Authors

Alexandra NelsoniD· 2 shared Emily L TwedelliD· 2 shared Allison E. GirasoleiD· 1 shared Andrew J. FloresiD· 1 shared Charles R. GerfeniD· 1 shared Isabelle Gonzalez Montalvo· 1 shared Jasmine A Stansil· 1 shared Jonathan S. SchoriD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Alexandra NelsonORCID

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2 papers

Recent·Most cited

Excessive Firing of Dyskinesia-Associated Striatal Direct Pathway Neurons is Gated By Dopamine and Excitatory Synaptic Input

Michael Ryan, Allison E. Girasole, Andrew J. Flores, Emily L Twedell, Matthew M. McGregor, Rea J Brakaj, Ronald F. Paletzki, Thomas S. Hnasko, Charles R. Gerfen, Alexandra Nelson

The paper investigates how levodopa-induced dyskinesia is linked to increased activity in specific striatal direct pathway medium spiny neurons, driven by dopamine and excitatory inputs.

Cell Reports · Jul 17, 2024Peer-reviewedNeuroscience

Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice

Jonathan S. Schor, Isabelle Gonzalez Montalvo, Perry W.E. Spratt, Rea J Brakaj, Jasmine A Stansil, Emily L Twedell, Kevin J. Bender, Alexandra Nelson

This study uses calcium imaging and optical DBS in parkinsonian mice to show that STN DBS disrupts STN activity dynamics, not inhibition or antidromic activation, to relieve motor symptoms.

eLife · Jul 4, 2022Peer-reviewedNeuroscience