Author
Alector (United States)
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Dalya Rosner, Jiahong Sun, Rita Cacace…·Arnon Rosenthal
This study shows that MS4A4A and MS4A6A negatively regulate TREM2 and microglial function in Alzheimer's disease, suggesting they are potential drug targets.
Rebecca Y. Wang, Glenn G. Wozniak, Xiaoting Wang…·Daniel R. Gulbranson
The paper uses CRISPR screens and Perturb-seq to identify gene programs and functional relationships in AD GWAS risk genes related to lipid and lysosomal pathways.
Jiqing Zhu, Rebecca Y. Wang, Xiaoting Wang…·Zia Khan
This paper introduces llm2geneset, a framework using large language models to generate gene sets from input genes and context, improving overrepresentation analysis compared to human-curated databases.
Gina M. Turco, Christie Chang, Rebecca Y. Wang…·Anastasia Baryshnikova
The paper aggregates and analyzes phenotypic data from yeast knock-out screens to identify gene functions and relationships, revealing new biological insights.
Michelle Chan, Han Yuan, Ilya Soifer…·David G. Hendrickson
The paper analyzes replicative senescence in WI-38 cells using multi-omics data, finding early senescence markers, myofibroblast-like transitions, and YAP1/TEAD1 regulation.
Yuko Arita, Griffin Kim, Zhijian Li…·R. Scott McIsaac
The paper develops YETI, a yeast library with inducible gene expression, and shows low native expression can bias promoter-perturbing screens.