ER Ca2+-levels control neuromodulator secretion by regulating L-type Ca2+-channel activity via its STIM1-interacting domain
Rein I. Hoogstraaten, Ruud F. G. Toonen, Matthijs Verhage
The paper shows that ER Ca2+ depletion in mouse neurons reduces DCV exocytosis by inhibiting L-type Ca2+ channels via a STIM1-dependent feedback loop, while not affecting SV exocytosis.