Author

Reyut Lewis

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adi Gershon· 1 shared Akanksha KhorgadeiD· 1 shared Aron PopovtzeriD· 1 shared Aveksha SharmaiD· 1 shared Aziz M. Al’KhafajiiD· 1 shared Cyrille J. CoheniD· 1 shared Eden EngaliD· 1 shared Elad ZismaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Adi Gershon

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2 papers

Recent·Most cited

RNA splicing dynamics in CD8 T cells uncovers isoforms that impact T cell-mediated cancer immunotherapy

Shay Tzaban, Priyanga Appasamy, Elad Zisman, Shiri Klein, Reyut Lewis, Houlin Yu, Akanksha Khorgade, Marc A. Schwartz, Moshe Sade-Feldman, Thomas Eisenhaure, Oren Parnas, Aron Popovtzer, Cyrille J. Cohen, Eric Shifrut, Aziz M. Al’Khafaji, , Michal Lotem

The paper constructs a single-cell splicing atlas of human CD8 T cells and identifies isoform-specific immune checkpoints that enhance effector function and tumor control.

bioRxiv · Sep 7, 2025 · PreprintImmunology

SMCHD1 loss triggers DUX4 expression by disrupting splicing in FSHD2

Eden Engal, Aveksha Sharma, Uria Aviel, Nadeen Taqatqa, Sarah Juster, Shiri Jaffe‐Herman, Mercedes Bentata, Ophir Geminder, Adi Gershon, Reyut Lewis, Gillian Kay, Merav Hecht, Silvina Epsztejn‐Litman, Marc Gotkine, Vincent Mouly, , Yotam Drier

This study shows SMCHD1 loss causes DUX4 expression in FSHD2 by disrupting splicing of DNMT3B, leading to hypomethylation and muscle abnormalities.

Science Advances · May 29, 2024Peer-reviewedGenomics