Author

Richard A Axton

MRC Centre for Regenerative Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander MedvinskyiD· 2 shared Antonella FidanzaiD· 2 shared Lesley M. ForresteriD· 2 shared A. Helen Taylor· 1 shared Alice Helen Taylor· 1 shared Beth E. P. HendersoniD· 1 shared Jennifer E. Easterbrook· 1 shared Katrin OttersbachiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersDevelopmental Biology

Alexander MedvinskyORCID

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2 papers

Recent·Most cited

Modulation of Aplnr signaling is required during the development and maintenance of the hematopoietic system

Melany Jackson, A Fidanza, A. Helen Taylor, Рыбцов Станислав Александрович, Richard A Axton, Maria Kydonaki, Stephen E. Meek, Tom Burdon, Alexander Medvinsky, Lesley M. Forrester

This study shows that Aplnr signaling is essential for generating hematopoietic stem cell precursors during development but must be downregulated for their maintenance.

Stem Cell Reports · Mar 7, 2021Peer-reviewedDevelopmental Biology

Single cell transcriptome analysis reveals markers of naive and lineage-primed hematopoietic progenitors derived from human pluripotent stem cells.

Antonella Fidanza, Nicola Romanò, Prakash Ramachandran, Sara Tamagno, Martha Lopez‐Yrigoyen, Alice Helen Taylor, Jennifer E. Easterbrook, Beth E. P. Henderson, Richard A Axton, Neil Cowan Henderson, Alexander Medvinsky, Katrin Ottersbach, Lesley M. Forrester

The paper identifies markers of naive and lineage-primed hematopoietic progenitors from hPSCs using single-cell RNA sequencing and functional assays.

bioRxiv · Apr 11, 2019 · PreprintDevelopmental Biology