Human hepatic stellate cells orchestrate the accumulation and function of CD103+ tissue-resident CD8+ T-cells in liver fibrosis
George E. Finney, Daniel Brown Romero, Ginevra Pistocchi…·Laura J. Pallett
Author
Centre for Inflammation ResearchORCID 0000-0001-5996-2413Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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George E. Finney, Daniel Brown Romero, Ginevra Pistocchi…·Laura J. Pallett
Naruhiro Kimura, Man Chun Wong, Ben Higgins…·Wei‐Yu Lu
This study shows that regulatory T cells (Tregs) influence bile duct regeneration during cholangitis, and their stability is critical for reducing fibrosis and inflammation.
Julian Weihs, Fatima Baldo, Alessandra Cardinali…·Milad Rezvani
The paper combines stem cell models and computational predictions to identify flavin cofactors as therapeutic targets for metabolic liver dysfunction.
Anirudh Patir, Jack Barrington, Stefan Szymkowiak…·Barry W. McColl
This study examines how stroke alters myeloid cell composition and phenotypes in the brain, linking changes to cell origin, spatial organization, and brain connectivity.
Anirudh Patir, Anton G. Gossner, Prakash Ramachandran…·Musa A. Hassan
The paper uses single-cell RNA sequencing to show that CD16- monocytes are key in the transcriptional response of human monocytes to Toxoplasma infection, revealing transcriptional heterogeneity and cytokine secretion patterns.
Antonella Fidanza, Nicola Romanò, Prakash Ramachandran…·Lesley M. Forrester
The paper identifies markers of naive and lineage-primed hematopoietic progenitors from hPSCs using single-cell RNA sequencing and functional assays.