Author

Alexander Medvinsky

MRC Centre for Regenerative MedicineORCID 0000-0002-6071-7447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Antonella FidanzaiD· 2 shared Lesley M. ForresteriD· 2 shared Richard A Axton· 2 shared A. Helen Taylor· 1 shared Alice Helen Taylor· 1 shared Beth E. P. HendersoniD· 1 shared Jennifer E. Easterbrook· 1 shared Katrin OttersbachiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Antonella FidanzaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Modulation of Aplnr signaling is required during the development and maintenance of the hematopoietic system

Melany Jackson, A Fidanza, A. Helen Taylor, Рыбцов Станислав Александрович, Richard A Axton, Maria Kydonaki, Stephen E. Meek, Tom Burdon, Alexander Medvinsky, Lesley M. Forrester

This study shows that Aplnr signaling is essential for generating hematopoietic stem cell precursors during development but must be downregulated for their maintenance.

Stem Cell Reports · Mar 7, 2021Peer-reviewedDevelopmental Biology

Single cell transcriptome analysis reveals markers of naive and lineage-primed hematopoietic progenitors derived from human pluripotent stem cells.

Antonella Fidanza, Nicola Romanò, Prakash Ramachandran, Sara Tamagno, Martha Lopez‐Yrigoyen, Alice Helen Taylor, Jennifer E. Easterbrook, Beth E. P. Henderson, Richard A Axton, Neil Cowan Henderson, Alexander Medvinsky, Katrin Ottersbach, Lesley M. Forrester

The paper identifies markers of naive and lineage-primed hematopoietic progenitors from hPSCs using single-cell RNA sequencing and functional assays.

bioRxiv · Apr 11, 2019 · PreprintDevelopmental Biology