BiochemistryNature CommunicationsPeer-reviewed
Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway
Ian Cooney, Heidi L. Schubert, Karina Cedeno…·Peter S. Shen
This study visualizes the Cdc48 AAA+ ATPase unfolding pathway using structural snapshots, revealing a hand-over-hand mechanism and the sequential ATP hydrolysis and substrate interaction between D1 and D2 subunits.
15 citations