Imaging the extracellular matrix in live tissues and organisms with a glycan-binding fluorophore
Antonio Fiore, G. Yu, Jason J. Northey, Ronak H. Patel, Thomas A. Ravenscroft, Richard Ikegami, Wiert Kolkman, Pratik Kumar, Jonathan B. Grimm, Tanya L. Dilan, Virginia M.S. Ruetten, Misha B. Ahrens, Hari Shroff, Valerie Marie Weaver, Shaohe Wang, Kayvon Pedram
This paper introduces a fluorophore for imaging extracellular matrix in live tissues and organisms by binding to glycans, enabling nonperturbative and wash-free visualization.
Nature Methods · Feb 6, 2025Peer-reviewedBiochemistry