Kota Mizumoto

This study identifies the Wnt-calcium signaling pathway as essential for stereotyped neurite pruning in C. elegans, showing its regulation by lin-44/Wnt and involvement of unc-43/CaMKII and pkc-2/PKC.

The paper identifies a channel-independent role of UNC-9/Innexin in controlling presynaptic tiling in C. elegans GABAergic motor neurons.

This study identifies a postmitotic role for UNC-4 and UNC-37 in synaptic patterning of cholinergic motor neurons in C. elegans by inhibiting the Wnt pathway.

This study identifies a gradient-independent role of Wnt signaling in stereotyped neurite pruning in C. elegans motor neurons.

This study systematically analyzes ASD-associated genes in C. elegans, identifying phenotypic relationships and reversible impairments in habituation learning.

This study identifies Rap2 and TNIK as regulators of Plexin-dependent synaptic tiling in C. elegans, showing their role in restricting presynaptic assembly and forming tiled innervation.

This paper uses CRISPR-Cas9 in C. elegans to replace human genes and assess their function, showing it can classify disease variants accurately.