Author

Richard Joseph Sugrue

Nanyang Technological University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Boon Huan TaniD· 4 shared Biruhalem TayeiD· 1 shared CHRISTOPHER E. JEFFREEiD· 1 shared Jan KosińskiiD· 1 shared Richard Sutejo· 1 shared Roland Thünauer· 1 shared Sebastian Maurer‐StrohiD· 1 shared Soak Kuan Lai· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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4 shared papersMicrobiology

Boon Huan TanORCID

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5 papers

Recent·Most cited

Evidence for a biphasic mechanism of virus transmission of the human metapneumovirus in LLC-MK2 cell monolayers.

Tra Nguyen Huong, Boon Huan Tan, Richard Joseph Sugrue

This study shows HMPV transmission in LLC-MK2 cells occurs in two phases: initial cell-to-cell spread via virus filaments, followed by cell-free virus spread linked to membrane changes and signaling pathway activation.

bioRxiv · Jul 22, 2026 · PreprintMicrobiology

Evaluating the use of siRNA to silence the expression of the H5N2 virus polymerase genes as strategy to block the transmission of the avian H5N2 virus in mammalian cells.

Richard Sutejo, Boon Huan Tan, Richard Joseph Sugrue

This study evaluates siRNA targeting H5N2 virus polymerase genes to block virus transmission in mammalian cells, finding that effective siRNAs reduce mRNA levels and inhibit viral replication.

bioRxiv · May 5, 2026 · PreprintMicrobiology

Analysis of the surface topology of respiratory syncytial virus particles that form on the surface of virus-infected cells.

CHRISTOPHER E. JEFFREE, Thong Beng Lu, Boon Huan Tan, Richard Joseph Sugrue

This study uses electron and atomic force microscopy to image the surface topology of RSV filaments on infected cells, revealing structured domains and glycocalyx involvement.

Virology · Oct 31, 2025Peer-reviewedMicrobiology

Evidence that the cell glycocalyx envelops respiratory syncytial virus (RSV) particles that form on the surface of RSV-infected human airway cells.

Soak Kuan Lai, Zhi Qi Lee, Ti-Myen Tan, Boon Huan Tan, Richard Joseph Sugrue

The paper shows that the glycocalyx envelops RSV particles as they form on infected cells, with HS and SYND4 on the virus surface.

Virology · Jan 18, 2025Peer-reviewedMicrobiology

Identifying repurposed drugs with moderate anti-influenza virus activity through computational prioritization of drug-target pairs

Biruhalem Taye, Roland Thünauer, Richard Joseph Sugrue, Sebastian Maurer‐Stroh, Jan Kosiński

This study identifies potential antiviral drugs against influenza virus by computationally prioritizing drug-target pairs and validating their activity in cell lines.

bioRxiv · Jul 31, 2023 · PreprintSystems Biology