Author

Robert Humphrey

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander K. WinkeliD· 1 shared Andrea DimitracopoulosiD· 1 shared Claire S. DurrantiD· 1 shared Daniel HaarhoffiD· 1 shared Eva K. PillaiiD· 1 shared Eva KreysingiD· 1 shared Hélène O. B. GautieriD· 1 shared Katrin A. Mooslehner· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Alexander K. WinkelORCID

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2 papers

Recent·Most cited

Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity

Eva Kreysing, Hélène O. B. Gautier, Sudipta Mukherjee, Katrin A. Mooslehner, Leila Mureşan, Daniel Haarhoff, Xiaohui Zhao, Alexander K. Winkel, Tina Boric, Sebastián Vásquez-Sepúlveda, Niklas Gampl, Andrea Dimitracopoulos, Eva K. Pillai, Robert Humphrey, Ragnhildur Thóra Káradóttir, Kristian Franze

This study shows that substrate stiffness affects neuronal maturation by regulating Piezo1-mediated TTR activity, delaying synapse formation and electrical maturation.

bioRxiv · Jul 25, 2024 · PreprintDevelopmental Biology

Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice cultures

Olivia Sheppard, Robert Humphrey, Claire S. Durrant, Michael P. Coleman

This study shows that lowering glucose increases Aβ levels in mouse brain slices and human cells, likely via BACE1 activation, but not in hypoxia conditions.

bioRxiv · Mar 12, 2024 · PreprintNeuroscience