Alexander K. Winkel

This study visualizes actin conformation dynamics in CTLs and shows they precede force generation during immune synapse formation.

The paper shows that mechanical signals regulate long-range chemical signaling in the developing Xenopus brain by modulating tissue stiffness and expression of guidance cues.

This study investigates how measurement force, speed, post-mortem time, and temperature affect the grey-to-white-matter elasticity ratio in spinal cord tissue, identifying parameter-dependent variations.

This study identifies how tissue mechanics and hyaluronic acid regulate digit tip regeneration by modulating ECM composition and cell behavior.

This study shows that substrate stiffness affects neuronal maturation by regulating Piezo1-mediated TTR activity, delaying synapse formation and electrical maturation.

This study shows that Plakoglobin regulates naive pluripotency in mouse ESCs through mechanosensitivity, with expression specific to the blastocyst stage in human and mouse embryos.

The paper identifies dynamic cell surface fluctuations as a key factor in early embryonic lineage sorting, showing that increased surface fluctuations in primitive endoderm precursors drive their segregation from epiblast precursors.