Author

Robert M. McKiernan

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:yeast· 2 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Tom EllisiD· 2 shared Andrew R. HeskethiD· 1 shared Benjamin A. BlountiD· 1 shared Dejana Jovicevic· 1 shared Evgenii LobzaeviD· 1 shared Fiachra Sweeney· 1 shared Giovanni StracquadanioiD· 1 shared Glen-Oliver F. GowersiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Tom EllisORCID

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2 papers

Recent·Most cited

Synthetic yeast chromosome XI design enables extrachromosomal circular DNA formation on demand

Benjamin A. Blount, Xinyu Lu, Maureen R M Driessen, Dejana Jovicevic, Mateo I Sanchez, Klaudia Ciurkot, Yu Zhao, Stephanie L. Lauer, Robert M. McKiernan, Glen-Oliver F. Gowers, Fiachra Sweeney, Viola Fanfani, Evgenii Lobzaev, Kim Palacios-Flores, Roy S. K. Walker, , Tom Ellis

The paper constructs a synthetic yeast chromosome XI and demonstrates how non-coding DNA modifications affect cell fitness, enabling on-demand extrachromosomal circular DNA formation.

bioRxiv · Jul 15, 2022 · PreprintSynthetic Biology

Rational Design Of RNA Structures That Predictably Tune Eukaryotic Gene Expression

Tim Weenink, Robert M. McKiernan, Tom Ellis

This paper designs RNA hairpin structures to predictably tune gene expression in yeast by modulating translation initiation efficiency, outperforming promoter mutation approaches.

bioRxiv · May 14, 2017 · PreprintSynthetic Biology