Author

Robert W. Hsieh

Institute for Stem Cell Biology and Regenerative Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Aaron M. NewmaniD· 2 shared Angera H. KuoiD· 2 shared Dalong QianiD· 2 shared Ferenc A. ScheereniD· 2 shared Frederick M. DirbasiD· 2 shared Michael F. ClarkeiD· 2 shared Shaheen S. SikandariD· 2 shared Ajit Jadhav· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Aaron M. NewmanORCID

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2 papers

Recent·Most cited

Single-cell transcriptional diversity is a hallmark of developmental potential

Gunsagar Singh Gulati, Shaheen S. Sikandar, Daniel J. Wesche, Anoop Manjunath, Anjan Bharadwaj, Mark J. Berger, Francisco Ilagan, Angera H. Kuo, Robert W. Hsieh, Shang Cai, Maider Zabala, Ferenc A. Scheeren, Neethan A. Lobo, Dalong Qian, Feiqiao Brian Yu, , Aaron M. Newman

The paper introduces CytoTRACE, a method using transcriptional diversity to predict differentiation states from scRNA-seq data, outperforming existing methods and identifying stem cells and tumor-related genes.

Science · Jan 23, 2020Peer-reviewedGenomics

CDK19 is a Regulator of Triple-Negative Breast Cancer Growth

Robert W. Hsieh, Angera H. Kuo, Ferenc A. Scheeren, Mark A. Zarnegar, Shaheen S. Sikandar, Jane Antony, Luuk S. Heitink, Divya Periyakoil, Tomer Kalisky, Sopheak Sim, Dalong Qian, Sanjay V. Malhotra, George Somlo, Frederick M. Dirbas, Ajit Jadhav, , Michael F. Clarke

This study identifies CDK19 as a therapeutic target for TNBC by showing its role in tumor growth and metastasis, with minimal impact on normal cells.

bioRxiv · May 10, 2018 · PreprintCancer Biology