Frederick M. Dirbas

This study identifies BCL11B as a determinant of chemoresistance in breast cancer, showing it promotes a persister state that TNFα can reverse.

This study shows FLASH radiotherapy reduces radiation-induced mucositis in a mouse model of Fanconi anemia compared to conventional radiotherapy.

This study compares FLASH and conventional dose rate radiotherapy in a murine breast cancer model, finding comparable tumor control with FLASH achieving higher eradication rates at 30 Gy in small tumors.

The paper introduces CytoTRACE, a method using transcriptional diversity to predict differentiation states from scRNA-seq data, outperforming existing methods and identifying stem cells and tumor-related genes.

This study identifies CDK19 as a therapeutic target for TNBC by showing its role in tumor growth and metastasis, with minimal impact on normal cells.