Ferenc A. Scheeren

The paper introduces a temperature-based peptide exchange method for loading different peptides into MHC-I multimers for HLA-A, B, and C alleles, enabling high-throughput T cell response analysis.

The paper designs and characterizes DNA origami nanostructures decorated with SC-TRAIL complexes to enhance TNFR activation and cell killing in Jurkat cells.

The paper introduces CytoTRACE, a method using transcriptional diversity to predict differentiation states from scRNA-seq data, outperforming existing methods and identifying stem cells and tumor-related genes.

This study identifies CDK19 as a therapeutic target for TNBC by showing its role in tumor growth and metastasis, with minimal impact on normal cells.