Roberto Jhonatan Olea‐Ozuna

This study identifies the functional interplay between PBP1A and LdtJ in Acinetobacter baumannii, showing that disrupting their coordination weakens the cell envelope and increases colistin resistance.

This study identifies disruption of the DNA repair protein RuvB as a mechanism promoting minocycline resistance in Acinetobacter baumannii through enhanced biofilm formation and extracellular DNA accumulation.

The paper shows that disrupting phospholipid homeostasis in Gram-negative bacteria enables LOS-deficient, colistin-resistant variants by altering outer membrane structure and peptidoglycan synthesis.

This study shows that the Tol-Pal system in Acinetobacter baumannii is conditionally required for envelope organization under specific environmental stresses but not under standard lab conditions.

The paper identifies a clinically silent resistance phenotype in Acinetobacter baumannii that allows survival during colistin therapy despite standard susceptibility testing.

This study identifies two functional ornithine lipid synthases in Vibrio cholerae and shows their roles in OL synthesis under phosphate limitation and low salinity.

This study shows that phosphate limitation in Gram-negative ESKAPE pathogens triggers alternative lipid synthesis, enabling antibiotic tolerance through reduced interaction with cationic antimicrobial peptides.

The paper identifies eleven genes involved in phospho-sphingolipid synthesis in Caulobacter crescentus, showing their role in membrane stability, antibiotic sensitivity, and virulence.