Sinjini Nandy

This study identifies OlsF-dependent ornithine lipid biosynthesis as a phosphate-responsive pathway that remodels the outer membrane and enhances polymyxin tolerance in Enterobacterales.

This study identifies the functional interplay between PBP1A and LdtJ in Acinetobacter baumannii, showing that disrupting their coordination weakens the cell envelope and increases colistin resistance.

The paper identifies a clinically silent resistance phenotype in Acinetobacter baumannii that allows survival during colistin therapy despite standard susceptibility testing.

This study investigates the role of LdtJ in Acinetobacter baumannii, showing its impact on peptidoglycan integrity and outer membrane lipid asymmetry, with defects suppressed by disrupting the Mla pathway.

This study shows that phosphate limitation in Gram-negative ESKAPE pathogens triggers alternative lipid synthesis, enabling antibiotic tolerance through reduced interaction with cationic antimicrobial peptides.