Molecular BiologyPLoS GeneticsPeer-reviewed
Bidirectional cooperation between Ubtf1 and SL1 determines RNA Polymerase I promoter recognition in cell and is negatively affected in the UBTF-E210K neuroregression syndrome.
Michel G. Tremblay, Dany S. Sibai, Mélissa Valere…·Tom Moss
The paper shows that UBTF1 and SL1 cooperate to enable RNA Polymerase I promoter recognition in rDNA, and this cooperation is disrupted in UBTF-E210K neuroregression syndrome.