Author

Dany S. Sibai

Université LavalORCID 0000-0001-8417-1111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Frédéric LessardiD· 2 shared Michel G. TremblayiD· 2 shared Tom MossiD· 2 shared Christophe TaviD· 1 shared Jean-Clément MarsiD· 1 shared Marianne Sabourin‐FélixiD· 1 shared Mark D. RobinsoniD· 1 shared Mark S. LeDouxiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Frédéric LessardORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 11, 2024

TTF1 control of LncRNA synthesis and cell growth delineates a tumour suppressor pathway acting directly on the ribosomal RNA Genes

Dany S. Sibai, Michel G. Tremblay, Frédéric Lessard…·Tom Moss

This study shows TTF1 regulates cell growth by blocking non-coding RNA synthesis from ribosomal gene promoters, thereby suppressing rRNA production and cell proliferation.

1 citation

humanmouse

𝕏 PostBluesky

Molecular BiologyPLoS GeneticsPeer-reviewedFeb 9, 2022

Bidirectional cooperation between Ubtf1 and SL1 determines RNA Polymerase I promoter recognition in cell and is negatively affected in the UBTF-E210K neuroregression syndrome.

Michel G. Tremblay, Dany S. Sibai, Mélissa Valere…·Tom Moss

The paper shows that UBTF1 and SL1 cooperate to enable RNA Polymerase I promoter recognition in rDNA, and this cooperation is disrupted in UBTF-E210K neuroregression syndrome.

22 citations

mousehuman

𝕏 PostBluesky