Author

Jean-Clément Mars

Institute for Research in Immunology and CancerORCID 0000-0001-8904-9502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Aidan W.B. Carlile· 1 shared Biljana-Culjkovic-Kraljacic· 1 shared Caleb M. EmbreeiD· 1 shared Dany S. SibaiiD· 1 shared Frédéric LessardiD· 1 shared Gokul Varma· 1 shared Katherine L. B. BordeniD· 1 shared Mark S. LeDouxiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Aidan W.B. Carlile

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2 papers

Recent·Most cited

Nuclear RNA cap-chaperones eIF4E and NCBP2 influence distinct mRNA fates

Jean-Clément Mars, Caleb M. Embree, Biljana-Culjkovic-Kraljacic, Gokul Varma, Naiyu Shi, Aidan W.B. Carlile, Patrick Gendron, Katherine L. B. Borden

The paper shows eIF4E and NCBP2 have distinct roles in nuclear mRNA processing, influencing different transcript populations and outcomes.

bioRxiv · Jul 25, 2025 · PreprintGenetics

Bidirectional cooperation between Ubtf1 and SL1 determines RNA Polymerase I promoter recognition in cell and is negatively affected in the UBTF-E210K neuroregression syndrome.

Michel G. Tremblay, Dany S. Sibai, Mélissa Valere, Jean-Clément Mars, Frédéric Lessard, Roderick T. Hori, Mohammad Moshahid Khan, Victor Y. Stefanovsky, Mark S. LeDoux, Tom Moss

The paper shows that UBTF1 and SL1 cooperate to enable RNA Polymerase I promoter recognition in rDNA, and this cooperation is disrupted in UBTF-E210K neuroregression syndrome.

PLoS Genetics · Feb 9, 2022Peer-reviewedMolecular Biology