Author

Roger A. Brooks

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrew W. McCaskieiD· 2 shared Eleftheria ZegginiiD· 2 shared Jeremy Mark WilkinsoniD· 2 shared Julia SteinbergiD· 2 shared Jyoti Sharma ChoudharyiD· 2 shared Karan Mehul ShahiD· 2 shared Matthew J. R. ClarkiD· 2 shared Raveen L. JayasuriyaiD· 2 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Andrew W. McCaskieORCID

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Author profile →

2 papers

Recent·Most cited

Decoding the genomic basis of osteoarthritis

Julia Steinberg, Lorraine Southam, Natalie C. Butterfield, Theodoros I. Roumeliotis, Andreas Fontalis, Matthew J. R. Clark, Raveen L. Jayasuriya, Diane Swift, Karan Mehul Shah, Katherine F. Curry, Roger A. Brooks, Andrew W. McCaskie, Christopher J. Lelliott, Jyoti Sharma Choudhary, J. H. Duncan Bassett, , Eleftheria Zeggini

This study identifies molecular subgroups of osteoarthritis and develops a 7-gene classifier to stratify patients, while uncovering potential therapeutic compounds.

bioRxiv · Jan 31, 2020 · PreprintGenomics

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

Julia Steinberg, Graham R. S. Ritchie, Theodoros I. Roumeliotis, Raveen L. Jayasuriya, Matthew J. R. Clark, Roger A. Brooks, Abbie L. A. Binch, Karan Mehul Shah, Rachael Coyle, Mercedes Pardo, Christine Lyn Le Maitre, Y.F. Ramos, Rob G. H. H. Nelissen, Ingrid Meulenbelt, Andrew W. McCaskie, , Eleftheria Zeggini

The paper identifies 49 genes and pathways associated with osteoarthritis progression using integrative epigenomics, transcriptomics, and proteomics in human chondrocytes from OA patients.

Scientific Reports · Aug 15, 2017Peer-reviewedSystems Biology