Author
University of DundeeORCID 0000-0001-5838-1086Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Paola Favuzza, Madeline G. Dans, Wenyin Su…·Alan F. Cowman
This study evaluates resistance development to PMX-selective and dual PMIX/X inhibitors in Plasmodium falciparum, finding that dual inhibitors have a higher resistance barrier.
Kathryn J. Wicht, John G. Woodland, Larnelle F. Garnie…·Kelly Chibale
This study shows that CHIR-124, a human Chk1 inhibitor, is active against Plasmodium falciparum through dual inhibition of PfArk1 and hemozoin formation, suggesting polypharmacology as a strategy for antimalarial drugs.
Christopher Bower-Lepts, Mukul Rawat, William Collins Keith…·Julian C. Rayner
This paper develops a chemogenomic platform using Plasmodium berghei artificial chromosomes to identify antimalarial drug targets through barcode sequencing and validation in Plasmodium falciparum.
Julia Steinberg, Graham R. S. Ritchie, Theodoros I. Roumeliotis…·Eleftheria Zeggini
The paper identifies 49 genes and pathways associated with osteoarthritis progression using integrative epigenomics, transcriptomics, and proteomics in human chondrocytes from OA patients.