NeuroscienceDiabetesPeer-reviewed
Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decreases ISR activation in DRG neurons
Muhammad Saad Yousuf, Marisol Mancilla Moreno, Brodie J Woodall…·Theodore John Price
This paper shows that diroximel fumarate (DRF) reduces MGO-induced pain hypersensitivity in mice by activating Nrf2 and decreasing ISR activation in DRG neurons.