Author

Ronald A. Ghossein

Memorial Sloan Kettering Cancer CenterPrimary ORCID profile (0000-0003-2802-8489 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Ronald A. GhosseiniD1 paper · Memorial Sloan Kettering Cancer Center

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Alan Loh HoiD· 1 shared Bin XuiD· 1 shared Elisa de StanchinaiD· 1 shared Eric Jeffrey ShermaniD· 1 shared Gnana Prakasam KrishnamoorthyiD· 1 shared James A. FaginiD· 1 shared Jeffrey A. KnaufiD· 1 shared Jena D. FrenchiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Alan Loh HoORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Loss of tumor cell MHC Class II drives insensitivity of BRAF-mutant anaplastic thyroid cancers to MAPK inhibitors

Vera Tiedje, Jillian Greenberg, Tianyue Qin, Soo-Yeon Im, Gnana Prakasam Krishnamoorthy, Laura Boucai, Bin Xu, Jena D. French, Eric Jeffrey Sherman, Alan Loh Ho, Elisa de Stanchina, Nicholas D. Socci, Jian Jun Jin, Ronald A. Ghossein, Jeffrey A. Knauf, , James A. Fagin

This study shows that loss of MHC Class II in BRAF-mutant anaplastic thyroid cancers leads to resistance to MAPK inhibitors by reducing CD4+ T-cell activation.

Journal of Clinical Investigation · Aug 19, 2025Peer-reviewedCancer Biology