Author

Ronald Lakony

University of Rochester Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Laura Maria CalviiD· 3 shared Cameron W. A. SnyderiD· 2 shared Elizabeth Pritchett· 2 shared Jeevisha BajajiD· 2 shared Kyukwang KimiD· 2 shared Manoj Kumar Khera· 2 shared Mark Anderson· 2 shared Michael W. BeckeriD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Laura Maria CalviORCID

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Author profile →

4 papers

Recent·Most cited

Local delivery of SBRT and IL-12 to Murine PDAC Tumors Modulates Hematopoiesis

Tara G Vrooman, Emily R. Quarato, Gary Hannon, Noah Salama, Maggie L. Lesch, Angela L. Hughson, Vedika S. Chandak, Nataliia Vdovichenko, Zhiming Jin, Ronald Lakony, Jian Ye, Sarah L Eckl, Sidney Lesser, Edith M. Lord, David C. Linehan, , Scott A. Gerber

This study shows that local delivery of SBRT and IL-12 to PDAC tumors in mice affects bone marrow hematopoiesis, causing both acute and long-term changes.

OncoImmunology · Jun 5, 2026Peer-reviewedImmunology

IL1β/IL1R1/IRAK4 Drives Inflammatory Ovarian Cancer Seeding at the inflamed sites and Is Reversed by an IRAK4 inhibitor UR241-2

J. Miller, Kyukwang Kim, Cameron W. A. Snyder, Negar Khazan, Niloy A. Singh, Megan E. Boyer, Elizabeth A. LaMere, Myla Strawderman, Sonali Sharma, Ronald Lakony, Michelle Whittum, Mark Anderson, Rick Keenan, Elizabeth Pritchett, Cameron Baker, , Rakesh K. Singh

This paper identifies the IL1β/IL1R1/IRAK4 axis as critical for inflammation-driven ovarian cancer metastasis and shows that IRAK4 inhibition with UR241-2 reduces tumor seeding and activates antitumor immune responses.

bioRxiv · May 5, 2026 · PreprintCancer Biology

IL-1β/IRAK4 Axis Promotes Ovarian Tumor Development at the Mesothelium Injury Sites

John P. Miller, Kyukwang Kim, Negar Khazan, Cameron W. A. Snyder, Niloy A. Singh, Elizabeth Lamere, Myla S. Strawderman, Sonali Sharma, Ronald Lakony, Michelle Whittum, Mark Anderson, Rick Keenan, Elizabeth Pritchett, Cameron D. Baker, John M. Ashton, , Rakesh K. Singh

This paper develops a MIM model to study EOC metastasis at mesothelial injury sites and shows IRAK4 inhibitors reduce tumor burden more effectively than IL-1/IL-1R1 targeting agents.

bioRxiv · Mar 18, 2025 · PreprintCancer Biology

Feasibility of Measuring Magnetic Resonance Elastography-derived Stiffness in Human Thoracic Aorta and Aortic Dissection Phantoms

Adnan A. Hirad, Faisal S. Fakhouri, Brian D. Raterman, Ronald Lakony, Maxwell B. Wang, Dakota W. Gonring, Baqir J. Kedwai, Arunark Kolipaka, Doran Mix

This paper tests the feasibility of using magnetic resonance elastography (MRE) to measure stiffness in thoracic aorta and aortic dissection phantoms to distinguish high-risk from stable dissections.

Journal of Vascular Surgery Cases and Innovative Techniques · Nov 30, 2024Peer-reviewedBioengineering