STING agonist-mediated endothelial cell activation drives NK cells and neutrophils-dependent pulmonary inflammation
Chen Chen, Yaqi Zhao, Fengyu Du, Rongchen Liu, Xinhang Zheng, Shanna Wu, Yiting Wang, Fengru Qiu, Liying Chen, Runqiu Chen, Fanglin Li, Likun Gong, Yiru Long
This study identifies the endothelial cell-NK cell-neutrophil axis as a key driver of STING agonist-induced pulmonary inflammation and toxicity.
bioRxiv · Mar 12, 2026 · PreprintPharmacology & Toxicology