Author

Roni R. Hyman

Broad Institute

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Cancer Biology· 1

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Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew Castillo· 1 shared Daniel ZeveiD· 1 shared David T. BreaultiD· 1 shared Ena Oreskovic· 1 shared Jason Daniel BuenrostroiD· 1 shared Karina Sharma· 1 shared Lety Ojeda-MironiD· 1 shared Ömer H. YilmaziD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew Castillo

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1 paper

Recent·Most cited

Clonal memory of colitis accumulates and promotes tumor growth

Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, Yan Hu, Daniel Zeve, Karina Sharma, Roni R. Hyman, Qiming Zhang, Andrew Castillo, David T. Breault, Ömer H. Yilmaz, Jason Daniel Buenrostro

The paper shows that colitis leaves an epigenetic memory in colonic stem cells that promotes tumor growth by enhancing regenerative gene programs and AP-1 activity.

bioRxiv · Feb 13, 2025 · PreprintCancer Biology