THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
Taylar Hammond, Jong Bin Choi, Miles W. Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard, Jan Marcel Skotheim, Peter K. Jackson, Anca M. Pașca, Seth M. Rubin, Julien Sage
This study identifies FAM53C as a regulator of the G1/S cell cycle transition, showing it interacts with DYRK1A and affects cell cycle progression in cultured cells and organoids.
eLife · Apr 30, 2026Peer-reviewedCell Biology