Griffin G. Hartmann

This study identifies a novel intermediate cell state and a regulatory network in SCLC that drives lineage plasticity and immunogenicity.

This study identifies FAM53C as a regulator of the G1/S cell cycle transition, showing it interacts with DYRK1A and affects cell cycle progression in cultured cells and organoids.

In vivo lineage tracing and targeted ablation in autochthonous mouse lung adenocarcinoma establish the Slc4a11+ high-plasticity cell state as a bidirectional transition hub driving tumor progression and therapy resistance.

The paper identifies a convergent node in male Drosophila olfactory circuits that regulates courtship behavior using the ds-Tango tool.

This study develops a novel transgenic mouse model of fibrolamellar hepatocellular carcinoma (FLC) and highlights challenges in establishing ex vivo cell models from FLC tumors.

This study shows that BDNF-TrkB signaling promotes malignant synaptic plasticity in gliomas, enhancing tumor progression through mechanisms similar to long-term potentiation in the healthy brain.

The paper identifies two enhancers critical for TAAR gene expression in olfactory sensory neurons and shows they operate in cis to regulate gene choice.

The paper identifies distinct second-order gustatory projection neurons in Drosophila that respond to sweet and bitter tastants, revealing a distributed coding scheme rather than a labeled-line model.